myasthenia gravis is neuromuscular disorder caused due to autoimmune production of antibodies against our nictotinic acetylcholine receptors. make makes acetylcholine fails to reach.
men at age 20 to 30
women age 50 to 70. females are common than males.
skeletal muscle weakness.
-improve with rest.-rest helps to increase acth
-days goes patient becomes weak-as day run acth will be reduced because as you use you loose.
-extraocular muscles are initally affected
difficulty in speaking.-dysarthria.
difficulty in chewing .
sensory and deep tendon reflex is not affected.
myasthenic crisis-when respiratory muscles are affected patient cant breath. emergency condition.
acetylcholine receptor antibody test(specific)
ct scan(rule out thymoma)
iv immunoglobulin therapy.