Wegener’s granulomatosis and microscopic polyangiitis

Wegener’s granulomatosis (also known as granulomatosis with polyangiitis) is a type of vasculitis that affects small and medium blood vessels. Symptoms can include saddle nose deformity, chronic sinusitis, and collapsed trachea. Microscopic polyangiitis is similar to wegener’s granulomatosis except it only affects small blood vessels in the lungs or kidneys. Learn how the presence of granulomas and antibodies (cANCA and pANCA) differentiate these two conditions.
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Goodpasture syndrome (Medical Condition)

Symptoms, risk factors and treatments of Goodpasture syndrome (Medical Condition)

Goodpasture syndrome is a rare autoimmune disease in which antibodies attack the lungs and kidneys, leading to bleeding from the lungs and to kidney failure

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Goodpasture syndrome

Goodpasture syndrome (GPS; also known as Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the lungs and kidneys, leading to bleeding from the lungs and to kidney failure. It may quickly result in permanent lung and kidney damage, often leading to death. It is treated with immunosuppressant drugs such as corticosteroids and cyclophosphamide, and with plasmapheresis, in which the antibodies are removed from the blood.
The disease was first described by the American pathologist Ernest Goodpasture of Vanderbilt University, in 1919 and was later named in his honour.

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Goodpasture Syndrome

Goodpasture Syndrome
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