Lester Mertz, M.D., rheumatologist at Mayo Clinic in Arizona, discusses an FDA approved, longitudinal protocol of patients with granulomatosis and polyangiitis as well as microscopic polyangiitis who are treated with a relatively new treatment. The study will help determine more accurately the benefit and side effect profile of this treatment.

Dr. Mertz and his colleagues at Mayo Clinic in Rochester and Mayo Clinic in Jacksonville are currently enrolling patients in this study. For more information, please visit http://clinicaltrials.mayo.edu/trial-details.cfm?trial_id=100929.

What is vasculitis? Vasculitis is an inflammation of the blood vessels that typically has some immune system-related cause. This video covers the pathophysiology of vasculitis in general, as well as more specific conditions like giant cell arteritis, Takayasu arteritis, Kawasaki disease, polyarteritis nodosa, Buerger’s disease, granulomatosis with polyangiitis, microscopic polyangiitis, and Churg-Strauss syndrome, as well as the different signs and symptoms between them.

Subscribe – http://www.youtube.com/channel/UCNI0qOojpkhsUtaQ4_2NUhQ?sub_confirmation=1

This video is brought to you by Osmosis. Along with providing open-access videos, Osmosis offers a comprehensive e-learning platform that connects med students with thousands of flashcards and quiz questions, depending on each student’s needs. Ever wish information would just diffuse into your brain? Well, Osmosis helps make that possible—don’t learn it, osmose it!

https://www.osmosis.org/

Support us on Patreon! – https://goo.gl/izRx2z

We also have free practice questions for the USMLE and NCLEX-RN exams here: https://goo.gl/3oGOEi

Also, we’re social:

Facebook – https://www.facebook.com/OsmoseIt/
Twitter – https://twitter.com/osmoseit

Got feedback? We’d love to hear it!

http://goo.gl/forms/T6de48NVzR

This video is licensed under a Creative Commons CC-BY-SA 4.0 international license, which means that you’re free to share and adapt it so long as you follow the Attribution and ShareAlike terms and conditions!

Credits:
Audio/visuals: Tanner Marshall, MS
Script: Kyle Slinn, RN
Reviewer: Rishi Desai, MD, MPH

Attributions:
Giant cell arteritis histology by ‘Nephron’ – https://commons.wikimedia.org/wiki/File:Giant_cell_arteritis_–_low_mag.jpg
Henoch-Schonlein Purpura image by ‘Hektor’ – https://en.wikipedia.org/wiki/Henoch%E2%80%93Sch%C3%B6nlein_purpura#/media/File:Purpura.jpg

Vasculitis (plural: vasculitides) is a group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Lymphangitis is sometimes considered a type of vasculitis. Vasculitis is primarily caused by leukocyte migration and resultant damage.
Although both occur in vasculitis, inflammation of veins (phlebitis) or arteries (arteritis) on their own are separate entities.

This video is targeted to blind users.

Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video

Wegener’s granulomatosis (also known as granulomatosis with polyangiitis) is a type of vasculitis that affects small and medium blood vessels. Symptoms can include saddle nose deformity, chronic sinusitis, and collapsed trachea. Microscopic polyangiitis is similar to wegener’s granulomatosis except it only affects small blood vessels in the lungs or kidneys. Learn how the presence of granulomas and antibodies (cANCA and pANCA) differentiate these two conditions.
More free lessons at: http://www.khanacademy.org/video?v=Ax98k35h_jk

Practice questions related to these concepts here:
https://www.khanacademy.org/test-prep/NCLEX-RN/rn-cardiovascular-diseases/rn-vasculitis/e/vasculitis-quiz

Find more free videos, practice questions, and articles related to health and medicine, at: https://www.khanacademy.org/science/health-and-medicine

Subscribe to Khan Academy Medicine at: http://youtube.com/subscription_center?add_user=khanacademymedicine

These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Khan Academy video.

Symptoms, risk factors and treatments of Goodpasture syndrome (Medical Condition)

Goodpasture syndrome is a rare autoimmune disease in which antibodies attack the lungs and kidneys, leading to bleeding from the lungs and to kidney failure

This video contains general medical information If in doubt, always seek professional medical advice.
The medical information is not advice and should not be treated as such. The medical information is provided without any representations or warranties, express or implied. We do not warrant or represent that the medical information on this websiteis true, accurate, complete, current or non-misleading

Music: ‘Undaunted’ Kevin Macleod CC-BY-3.0
Source/Images: “Goodpasture syndrome” CC-BY-2.5 https://www.freebase.com/m/03yh_n

Prepare for USMLE,UK,CANADIAN,AUSTRALIAN, NURSING & OTHER MEDICAL BOARD examinations around the globe with us.Understand the basics, concepts and how to answer wisely and score 99 in each step. we are here to help you. What are you waiting for subscribe now!!!

SUBSCRIBE NOW: http://bit.ly/161OmbF

For Business inquiries: [email protected]

Join our USMLE step 1 prep Zone : https://www.facebook.com/groups/730000020375744

Join our USMLE CK STUDY GROUP: https://www.facebook.com/groups/320959178079398

Goodpasture syndrome (GPS; also known as Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the lungs and kidneys, leading to bleeding from the lungs and to kidney failure. It may quickly result in permanent lung and kidney damage, often leading to death. It is treated with immunosuppressant drugs such as corticosteroids and cyclophosphamide, and with plasmapheresis, in which the antibodies are removed from the blood.
The disease was first described by the American pathologist Ernest Goodpasture of Vanderbilt University, in 1919 and was later named in his honour.

This video is targeted to blind users.

Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video

Goodpasture Syndrome
Instructional Tutorial Video
CanadaQBank.com
QBanks for AMC Exams, MCCEE, MCCQE & USMLE

URL: http://youtu.be/S2Iotn0Hye0